BDBM581720 US11512080, Compound I-8::US11512080, Compound I-94

SMILES Clc1ccc2nc(SC3CCC(=O)NC3=O)[nH]c2c1

InChI Key InChIKey=QIBXNDFNYXFSIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581720   

TargetProtein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM581720(US11512080, Compound I-8 | US11512080, Compound I-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

TargetProtein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM581720(US11512080, Compound I-8 | US11512080, Compound I-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent