BDBM581980 WO2023287730, Compound P161-1.1
SMILES COc1cc2c(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)nn3cnnc3c2cc1OC
InChI Key InChIKey=LKQJUYZGEYWGHK-SNVBAGLBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 581980
TargetGTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Recurium Ip Holdings
WIPO
Recurium Ip Holdings
WIPO
Affinity DataIC50: 263nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair