BDBM581992 WO2023287730, Compound P171-1.1

SMILES CC(C)c1nnc2nc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c3CN(Cc3n12)C(=O)C1(C)COC1

InChI Key InChIKey=YSSDPWGYAHURKI-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581992   

TargetGTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Recurium Ip Holdings

WIPO
LigandPNGBDBM581992(WO2023287730, Compound P171-1.1)
Affinity DataIC50:  263nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed