BDBM581996 WO2023287730, Compound P172-1.1
SMILES C[C@@H](Nc1nc2nccn2c2ccc(Br)cc12)c1cccc(C(F)F)c1F
InChI Key InChIKey=FLSHVWHQWJHBIT-SNVBAGLBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 581996
TargetGTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Recurium Ip Holdings
WIPO
Recurium Ip Holdings
WIPO
Affinity DataIC50: <15nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair