BDBM581997 WO2023287730, Compound P172-2.1

SMILES C[C@@H](Nc1nc2nccn2c2ccc(cc12)C1=CCOCC1)c1cccc(c1C)C(F)(F)F

InChI Key InChIKey=AKMUFOUTNWYZCB-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581997   

TargetGTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Recurium Ip Holdings

WIPO
LigandPNGBDBM581997(WO2023287730, Compound P172-2.1)
Affinity DataIC50: <15nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed