BDBM582003 WO2023287730, Compound P172-2.4

SMILES C[C@@H](NC1=NC2=NCCN2c2ccc(cc12)C1=CCN(C)CC1)c1cc(N)cc(c1)C(F)(F)F

InChI Key InChIKey=GDXRSYXCWVRIEZ-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582003   

TargetGTPase KRas [2-169,G12C]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Recurium Ip Holdings

WIPO
LigandPNGBDBM582003(WO2023287730, Compound P172-2.4)
Affinity DataIC50: <15nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed