BDBM585309 3'-(4-(2,4-diaminopyrimidin-5- yl)piperazin-1-yl)-[1,1'- biphenyl]-3-carbonitrile::US11530198, Example 67

SMILES Nc1ncc(N2CCN(CC2)c2cccc(c2)-c2cccc(c2)C#N)c(N)n1

InChI Key InChIKey=JKYCFAYZSLKOTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585309   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585309(US11530198, Example 67 | 3'-(4-(2,4-diaminopyrimid...)
Affinity DataIC50: 3.89nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent

TargetDihydrofolate reductase(Human)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585309(US11530198, Example 67 | 3'-(4-(2,4-diaminopyrimid...)
Affinity DataIC50: 302nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
US Patent