BDBM586078 US11530237, Compound 259::US11542297, Compound 259

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cnc(F)c1

InChI Key InChIKey=MIWMEAPAQSZRDV-LMSUEEHRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 586078   

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
Sage Therapeutics

US Patent
LigandPNGBDBM586078(US11530237, Compound 259 | US11542297, Compound 25...)
Affinity DataIC50:  300nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rattus norvegicus (rat))
Sage Therapeutics

US Patent
LigandPNGBDBM586078(US11530237, Compound 259 | US11542297, Compound 25...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rattus norvegicus)
Sage Therapeutics

US Patent
LigandPNGBDBM586078(US11530237, Compound 259 | US11542297, Compound 25...)
Affinity DataIC50: <10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent