BDBM587940 US11535621, Example 190

SMILES CN(C)CC#Cc1ccc(NC(=O)c2nc(nc3cc[nH]c23)-n2ccnc2)cc1

InChI Key InChIKey=ZLXDPHAHXPPSAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 587940   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587940(US11535621, Example 190)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent