BDBM588450 US11542275, Compound 72

SMILES CC(=O)N1C2CCC1CC(C2)c1ccc(CN2CCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)nc1

InChI Key InChIKey=GUIUFFZFWMAULA-JXOQWRPTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588450   

TargetProtein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588450(US11542275, Compound 72)
Affinity DataIC50:  19nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent