BDBM588466 US11542275, Compound 92

SMILES OC(CNC1Cc2ccccc2C1)CN1CCN(Cc2ccc(cn2)-c2cnc(nc2)C#N)C1=O

InChI Key InChIKey=WTOQODZRRMJZKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588466   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588466(US11542275, Compound 92)
Affinity DataIC50:  21nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent