BDBM590629 US11560381, Compound D428

SMILES [#6]-[#8]-c1cc(cc(-[#8]-[#6])c1-[#6]-[#7]-1-[#6]-[#6]C2([#6]-[#7](-[#6]2)-c2ccc3-[#6]-[#7](-[#6]-4-[#6]-[#6]-[#6](=O)-[#7]-[#6]-4=O)-[#6](=O)-c3c2)[#6]-[#6]-1)-c1cn(-[#6])c(=O)c2cncn12

InChI Key InChIKey=HMWVSLQOUQQYRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590629   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM590629(US11560381, Compound D428)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent