BDBM590642 US11560381, Compound D441

SMILES COc1cc(cc(OC)c1CN1CC(C1)C#Cc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O)-c1cc(C(F)F)c(=O)n(C)c1

InChI Key InChIKey=AREYJRLNRMLNHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590642   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM590642(US11560381, Compound D441)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent