BDBM590655 US11560381, Compound D454

SMILES C/C=C/Cn8cc(c6cc(OC)c(CN1CCC5(CC1)CN(c4ccc3CN(C2CCC(=O)NC2=O)C(=O)c3c4)C5)c(OC)c6)n7cncc7c8=O

InChI Key InChIKey=FRQKEQDXDMLBKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590655   

TargetProtein SSX2/Protein SSXT(Human)
Foghorn Therapeutics

US Patent
LigandPNGBDBM590655(US11560381, Compound D454)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent