BDBM591143 1-(8-amino-7-fluoro-6-(8-methyl- 2,3-dihydro-1H-pyrido[2,3- b][1,4]oxazin-7-yl)isoquinolin-3-yl)- 3-(cyclopropylmethyl)urea::US11566003, Compound 29

SMILES Cc1c2NCCOc2ncc1-c1cc2cc(NC(=O)NCC3CC3)ncc2c(N)c1F

InChI Key InChIKey=JBKNNOURSCQBEV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 591143   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM591143(1-(8-amino-7-fluoro-6-(8-methyl- 2,3-dihydro-1H-py...)
Affinity DataKi:  0.0140nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent