BDBM5916 CHEMBL183025::N-[7-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)-3-oxo-2,3-dihydro-1H-isoindol-4-yl]benzamide::isoindolinone analog 14b

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc(NC(=O)c3ccccc3)c3C(=O)NCc23)c1

InChI Key InChIKey=WLYXXRYIFCMOEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5916   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM5916(N-[7-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)-...)
Affinity DataIC50: 470nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed