BDBM592311 2-[({2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-7-methyl-1,3-benzoxazol-5-yl}methyl)amino]ethanol::US11572366, Example 16

SMILES Cc1cc(CNCCO)cc2nc(oc12)-c1cccc(c1C)-c1ccc2OCCOc2c1

InChI Key InChIKey=MHIGPOAVCFTBOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 592311   

LigandPNGBDBM592311(2-[({2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-met...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM592311(2-[({2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-met...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed