BDBM592971 US11576897, Example 20

SMILES CNCc1cc(OCc2ccccc2F)n(CC2CCCCC2)n1

InChI Key InChIKey=KXEZUXJCVHYFBX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 592971   

Target5-hydroxytryptamine receptor 2A(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 592971BDBM592971(US11576897, Example 20 | US20260108494, Example 20)
Affinity DataKi:  0.650nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 592971BDBM592971(US11576897, Example 20 | US20260108494, Example 20)
Affinity DataKi:  0.650nMAssay Description:5-HT2A: A solution containing 50 μL of [H]-ketanserin (the final concentration: 1 nM), 2 μL of a solution of a test compound in DMSO or a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 592971BDBM592971(US11576897, Example 20 | US20260108494, Example 20)
Affinity DataKi:  1.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 592971BDBM592971(US11576897, Example 20 | US20260108494, Example 20)
Affinity DataKi:  1.60nMAssay Description:Specifically, a solution containing 50 μL of [3H]-citalopram (GE Healthcare) diluted with SERT buffer (50 mmol/L Tris-HCl (pH=7.4) containing 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 592971BDBM592971(US11576897, Example 20 | US20260108494, Example 20)
Affinity DataKi:  9nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 592971BDBM592971(US11576897, Example 20 | US20260108494, Example 20)
Affinity DataKi:  9nMAssay Description:5-HT2C: A solution containing 50 μL of [H]-mesulergine (GE Healthcare) diluted with 50 mmol/L Tris-HCl (pH=7.4) (the final concentration: about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent