BDBM593012 US11576897, Example 296

SMILES CNCc1cc(OCC2CC=CC=C2Cl)n(C(C)C2CCCCC2)n1

InChI Key InChIKey=NSESBWKIDFXENL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 593012   

TargetSodium-dependent serotonin transporter(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 593012BDBM593012(US11576897, Example 296 | US20260108494, Example 2...)
Affinity DataKi:  0.910nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 593012BDBM593012(US11576897, Example 296 | US20260108494, Example 2...)
Affinity DataKi:  0.910nMAssay Description:Specifically, a solution containing 50 μL of [3H]-citalopram (GE Healthcare) diluted with SERT buffer (50 mmol/L Tris-HCl (pH=7.4) containing 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 593012BDBM593012(US11576897, Example 296 | US20260108494, Example 2...)
Affinity DataKi:  2.10nMAssay Description:5-HT2A: A solution containing 50 μL of [H]-ketanserin (the final concentration: 1 nM), 2 μL of a solution of a test compound in DMSO or a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 593012BDBM593012(US11576897, Example 296 | US20260108494, Example 2...)
Affinity DataKi:  2.10nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 593012BDBM593012(US11576897, Example 296 | US20260108494, Example 2...)
Affinity DataKi:  6.20nMAssay Description:5-HT2C: A solution containing 50 μL of [H]-mesulergine (GE Healthcare) diluted with 50 mmol/L Tris-HCl (pH=7.4) (the final concentration: about ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 593012BDBM593012(US11576897, Example 296 | US20260108494, Example 2...)
Affinity DataKi:  6.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent