BDBM593050 2-(4-((4-((2-azaspiro[3.3]heptan-6- yl)methoxy)-5-chloropyrimidin-2- yl)amino)-3-methyl-1H-pyrazol-1- yl)-2-methylpropanenitrile::US11578061, Example 28

SMILES Cc1nn(cc1Nc1ncc(Cl)c(OCC2CC3(CNC3)C2)n1)C(C)(C)C#N

InChI Key InChIKey=REJNOOUBBUWCAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593050   

LigandPNGBDBM593050(2-(4-((4-((2-azaspiro[3.3]heptan-6- yl)methoxy)-5-...)
Affinity DataIC50: <50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent