BDBM593103 N-((1R,4R)-4-(((5-chloro-2-((1-(2- cyanopropan-2-yl)-3-methyl-1H- pyrazol-4-yl)amino)pyrimidin-4- yl)oxy)methyl)cyclohexyl) acetamide::US11578061, Example 81

SMILES CC(=O)N[C@H]1CC[C@H](COc2nc(Nc3cn(nc3C)C(C)(C)C#N)ncc2Cl)CC1

InChI Key InChIKey=DSIMQYQIJRPGQC-WKILWMFISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593103   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527](Homo sapiens (Human))
Halia Therapeutics

US Patent
LigandPNGBDBM593103(N-((1R,4R)-4-(((5-chloro-2-((1-(2- cyanopropan-2-y...)
Affinity DataIC50: <50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent