BDBM594640 2-(Thiazolo[4,5-b]pyridin-2-yl)-2,7-diazaspiro[4.5]decane-6,8-dione::US11584748, Example 7

SMILES O=C1CCC2(CCN(C2)c2nc3ncccc3s2)C(=O)N1

InChI Key InChIKey=JAMNHMJDAVFPED-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594640   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594640(2-(Thiazolo[4,5-b]pyridin-2-yl)-2,7-diazaspiro[4.5...)
Affinity DataKd: <1nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent