BDBM594671 2-(1H-Indazole-4-carbonyl)-2,7-diazaspiro[4.5]decane-6,8-dione::US11584748, Example 38

SMILES O=C1CCC2(CCN(C(=O)c3cccc4[nH]ncc34)C2)C(=O)N1

InChI Key InChIKey=IWRTVCYWLNFSLY-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594671   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594671BDBM594671(2-(1H-Indazole-4-carbonyl)-2,7-diazaspiro[4.5]deca...)
Affinity DataKd:  84nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent