BDBM594795 US11584755, Example 84

SMILES OC(=O)c1c(O)c(=O)n(Cc2cnn(c2)-c2ccccc2)c2ccsc12

InChI Key InChIKey=MOOBNIMNDWJPRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 594795   

TargetFlap endonuclease 1(Homo sapiens (Human))
Ideaya Biosciences

US Patent
LigandPNGBDBM594795(US11584755, Example 84)
Affinity DataIC50: <200nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Ideaya Biosciences

US Patent
LigandPNGBDBM594795(US11584755, Example 84)
Affinity DataIC50:  500nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetExonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594795(US11584755, Example 84)
Affinity DataIC50:  500nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent