BDBM594824 US11584755, Example 113

SMILES COc1ccc(cc1)-n1cc(Cn2c3ccsc3c(C(O)=O)c(O)c2=O)cn1

InChI Key InChIKey=JBUFLEUOSAEDQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 594824   

TargetFlap endonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594824(US11584755, Example 113)
Affinity DataIC50: <200nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDNA excision repair protein ERCC-5(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594824(US11584755, Example 113)
Affinity DataIC50:  1.50E+3nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetExonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594824(US11584755, Example 113)
Affinity DataIC50:  500nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent