BDBM595070 US11584714, Compound 1098

SMILES C[C@H](NC(=O)C1CC(CCN1)c1cccc(C)c1)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=NEGBOYIXRYPUIZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 595070   

TargetC-type lectin domain family 4 member K(Human)
Omeros

US Patent
LigandPNGBDBM595070(US11584714, Compound 1098 | US12195427, Compound 1...)
Affinity DataIC50: 50nMAssay Description:The MASP-2 assay utilizes a fluorogenic substrate, based on the cleavage site for its natural substrate C2. The assay was run at room temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595070(US11584714, Compound 1098 | US12195427, Compound 1...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay protocol was carried out as follows. Test compounds were serially diluted in DMSO and then 100 nL of each dilution was transferred t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595070(US11584714, Compound 1098 | US12195427, Compound 1...)
Affinity DataKi: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595070(US11584714, Compound 1098 | US12195427, Compound 1...)
Affinity DataKi: <500nMAssay Description:The MASP-2 assay utilizes a fluorogenic substrate, based on the cleavage site for its natural substrate C2. The assay was run at room temperature in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent