BDBM595600 US11591326, Compound 17a

SMILES CC(=O)N1CCC(CC1)Nc1cc2c(OCCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)cc1F

InChI Key InChIKey=MWCNXVXIACALFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 595600   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 595600BDBM595600(US11591326, Compound 17a)
Affinity DataIC50: 248nMAssay Description:General Procedure for PRMT5/MEP50 AlphaLISA Enzyme Inhibitory Assays: Assays were performed in the buffer consisting of 50 mM Tris, pH 8.5, 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent