BDBM595730 US11591331, Example 50

SMILES CCc1cc2ncc(CN3CCN(c4ccc(C(=O)NCCC#N)nc4)CC3)cc2[nH]c1=O

InChI Key InChIKey=UDGVGGOJPXRESF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595730   

TargetPoly [ADP-ribose] polymerase 1(Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 595730BDBM595730(US11591331, Example 50)
Affinity DataIC50: 7.30nMAssay Description:Assays based on fluorescent polarization (FP) have been widely utilized in drug discovery due to the homogenous format, robust performance and lack o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 595730BDBM595730(US11591331, Example 50)
Affinity DataIC50: 1.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent