BDBM596385 4-[(4-{3-cyano-2-[4-(7H- pyrrolo[2,3-d]pyrimidin- 4-yl)-1H-pyrazol-1- yl]propyl}piperazin-1- yl)carbonyl]-3- fluorobenzonitrile::US11596632, Comp. No. 8

SMILES N#CCC(CN1CCN(C(=O)c2ccc(C#N)cc2F)CC1)n1cc(-c2nccc3[nH]ccc23)cn1

InChI Key InChIKey=ZKBCBTKOSVYCKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596385   

TargetTyrosine-protein kinase JAK1(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 596385BDBM596385(US11596632, Comp. No. 8 | 4-[(4-{3-cyano-2-[4-(7H-...)
Affinity DataIC50: 10nMAssay Description:JAK1 pathway inhibitors that can be used for the treatment of cytokine-related diseases or disorders are tested for inhibitory activity of JAK target...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
US Patent