BDBM600598 (R)-1,1,1-Trifluoro-2-(5-(pyridin-4-ylmethyl)-1H-imidazol-2-yl)propan-2-ol and (S)-1,1,1-trifluoro-2-(5-(pyridin-4-ylmethyl)-1H-imidazol-2-yl)propan-2-ol::US11629136, Example 32

SMILES C[C@@](O)(C1NC=C(Cc2ccncc2)N1)C(F)(F)F

InChI Key InChIKey=ZJDAVEXTVVYMLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600598   

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600598((R)-1,1,1-Trifluoro-2-(5-(pyridin-4-ylmethyl)-1H-i...)
Affinity DataIC50: 1.00E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
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Date in BDB:
5/27/2023
Entry Details
US Patent