BDBM600600 (S)-4-((2-(2,2,2-trifluoro-1-methoxyethyl)-1H-imidazol-5-yl)methyl)pyridine and (R)-4-((2-(2,2,2-trifluoro-1-methoxyethyl)-1H-imidazol-5-yl)methyl)pyridine::US11629136, Example 33::US11629136, Example 33a

SMILES COC(c1ncc(Cc2ccncc2)[nH]1)C(F)(F)F

InChI Key InChIKey=ITEWSYMBUWTGNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600600   

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600600(US11629136, Example 33a | (S)-4-((2-(2,2,2-trifluo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600600(US11629136, Example 33a | (S)-4-((2-(2,2,2-trifluo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent