BDBM600690 US11629146, Compound 134::US11629146, Compound 135

SMILES C[C@@H](Oc1ncc(cc1F)-c1cn2c(nnc2cn1)C(F)F)C(F)(F)F

InChI Key InChIKey=DEVGYCWWUOPDSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600690   

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600690BDBM600690(US11629146, Compound 135 | US11629146, Compound 13...)
Affinity DataIC50: 3.00E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 600690BDBM600690(US11629146, Compound 135 | US11629146, Compound 13...)
Affinity DataIC50: 3.00E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent