BDBM60367 4-(3-methoxy-4-oxidanyl-phenyl)-3-methyl-6-oxidanylidene-1-phenyl-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile::4-(4-hydroxy-3-methoxy-phenyl)-6-keto-3-methyl-1-phenyl-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile::4-(4-hydroxy-3-methoxyphenyl)-3-methyl-6-oxo-1-phenyl-2H-pyrazolo[3,4-b]pyridine-5-carbonitrile::MLS000084073::SMR000048143::cid_666853

SMILES COc1cc(-c2c(C#N)c(=O)[nH]c3c2c(C)nn3-c2ccccc2)ccc1O

InChI Key InChIKey=YMXCONZIDIDWFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 60367   

TargetCaspase-9(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 60367BDBM60367(4-(3-methoxy-4-oxidanyl-phenyl)-3-methyl-6-oxidany...)
Affinity DataIC50: 1.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2012
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 60367BDBM60367(4-(3-methoxy-4-oxidanyl-phenyl)-3-methyl-6-oxidany...)
Affinity DataIC50: 2.05E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay
TargetLarge T antigen(SV40)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 60367BDBM60367(4-(3-methoxy-4-oxidanyl-phenyl)-3-methyl-6-oxidany...)
Affinity DataIC50: 1.00E+5nMAssay Description:A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetApoptotic protease-activating factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 60367BDBM60367(4-(3-methoxy-4-oxidanyl-phenyl)-3-methyl-6-oxidany...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2012
Entry Details
PCBioAssay