BDBM604048 US11660293, Example 152::US11660293, Example 154

SMILES C[C@@H]1C2CC(C2)N(C1CNc1nc2ccc(F)cc2s1)C(=O)c1nc(C)ccc1-n1nccn1

InChI Key InChIKey=UJGSPBJSTPPWNS-GAAFMGEWSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 604048   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604048(US11660293, Example 152 | US11660293, Example 154)
Affinity DataKi:  0.871nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604048(US11660293, Example 152 | US11660293, Example 154)
Affinity DataKi:  2.09nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604048(US11660293, Example 152 | US11660293, Example 154)
Affinity DataKi:  589nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Chronos Therapeutics

US Patent
LigandPNGBDBM604048(US11660293, Example 152 | US11660293, Example 154)
Affinity DataKi:  794nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent