BDBM60418 US9056847, Fluorophore 2-cyclophellitol

SMILES COc1ccc(cc1)C1=[N+]2C(C=C1)=C(CCCCc1cn(C[C@H]3[C@H]4O[C@H]4[C@H](O)[C@@H](O)[C@@H]3O)nn1)c1ccc(-c3ccc(OC)cc3)n1[B-]2(F)F

InChI Key InChIKey=OWVDUFOFLDIMAR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60418   

TargetLysosomal acid glucosylceramidase(Human)
Academisch Medisch Centrum Bij Universiteit Van Amsterdam

US Patent
LigandPNGBDBM60418(US9056847, Fluorophore 2-cyclophellitol)
Affinity DataKi:  1.56nMpH: 5.2Assay Description:Activity of GBA was measured at 37° C. with 4-methylumbelliferyl β-D-glucopyranoside as substrate as reported previously. To determine the IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent