BDBM60507 BDBM50054521::US9085531, 75

SMILES CN1CC(c2cc3ccccc3s2)c2ccc(cc2C1)N1CCOCC1

InChI Key InChIKey=ZRXUBWRDOKMUIN-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 60507   

LigandPNGBDBM60507(BDBM50054521 | US9085531, 75)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]-RTI-55 from recombinant SERT (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
LigandPNGBDBM60507(BDBM50054521 | US9085531, 75)
Affinity DataIC50: 5.80nMAssay Description:Displacement of [125I]-RTI-55 from recombinant DAT (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
LigandPNGBDBM60507(BDBM50054521 | US9085531, 75)
Affinity DataKi:  6.70nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

LigandPNGBDBM60507(BDBM50054521 | US9085531, 75)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]-RTI-55 from recombinant NET (unknown origin) expressed in HEK cells by saturation binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
LigandPNGBDBM60507(BDBM50054521 | US9085531, 75)
Affinity DataKi:  21.7nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

LigandPNGBDBM60507(BDBM50054521 | US9085531, 75)
Affinity DataKi:  284nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent