BDBM605840 US11680056, Example 22A::US11680056, Example 22B

SMILES Cc1cc(COc2cc(C)n(-c3cc(ncc3C)-c3ccnc(n3)C(C)(C)O)c(=O)c2Cl)ncc1F

InChI Key InChIKey=LIFVOTGTVLDGRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 605840   

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605840BDBM605840(US11680056, Example 22A | US11680056, Example 22B)
Affinity DataIC50: 31.6nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605840BDBM605840(US11680056, Example 22A | US11680056, Example 22B)
Affinity DataIC50: 1.00E+4nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605840BDBM605840(US11680056, Example 22A | US11680056, Example 22B)
Affinity DataIC50: 1.58E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605840BDBM605840(US11680056, Example 22A | US11680056, Example 22B)
Affinity DataIC50: 3.16E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent