BDBM605846 US11680056, Example 25A

SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1ccn(n1)C(C)(C)CO

InChI Key InChIKey=LTXSULWZIIMLEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605846   

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605846BDBM605846(US11680056, Example 25A)
Affinity DataIC50: 31.6nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605846BDBM605846(US11680056, Example 25A)
Affinity DataIC50: 3.16E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent