BDBM605856 US11680056, Example 30

SMILES Cc1nn(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1ccnc(n1)C(C)(C)O

InChI Key InChIKey=IVBWIJOUOJSXGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605856   

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605856BDBM605856(US11680056, Example 30)
Affinity DataIC50: 631nMAssay Description:This study evaluates the inhibitory potency of invention compound on p38/MK2 pathway vs p38/PRAK pathway. More specially the compound concentration (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 2 [46-400](Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 605856BDBM605856(US11680056, Example 30)
Affinity DataIC50: 2.51E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent