BDBM606781 US11685732, Compound I-449

SMILES CC([C@H]1CC[C@H](N)CC1)S(=O)(=O)NNC(=O)c1cc(-c2cn(C)cn2)cc(Cl)c1F

InChI Key InChIKey=IHFUQMUFOIWXKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 606781   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Epizyme

US Patent
LigandChemical structure of BindingDB Monomer ID 606781BDBM606781(US11685732, Compound I-449)
Affinity DataIC50: 1.00E+5nMAssay Description:KAT-6A. Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2023
Entry Details
US Patent