BDBM60704 BDBM183583::US9145354, 220::US9145354, 267

SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(N)c(Cl)c2)c1F

InChI Key InChIKey=ZZBNFNAKEHKZDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60704   

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM60704(US9145354, 220 | US9145354, 267 | BDBM183583)
Affinity DataIC50: 85nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM60704(US9145354, 220 | US9145354, 267 | BDBM183583)
Affinity DataIC50: 140nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM60704(US9145354, 220 | US9145354, 267 | BDBM183583)
Affinity DataIC50: 260nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent