BDBM608350 (Z)-15-chloro-13-ethyl-21,25,61-trimethyl- 11H,21H,61H-10-oxa-4,8-dithia-1(4,1)-indola- 2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 8

SMILES CCc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CSCc5nn(C)c(C)c5-c5c(Cl)ccc2c15)nn4C)cc1ccccc31

InChI Key InChIKey=NCFZECMJNRKDBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608350   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608350((Z)-15-chloro-13-ethyl-21,25,61-trimethyl- 11H,21H...)
Affinity DataIC50:  21nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent