BDBM608351 (Z)-13,15-dichloro-21,25,61-trimethyl- 11H,21H,61H-10-oxa-4,8-dithia-1(4,1)-indola- 2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 9

SMILES Cc1c-2c(CSCc3cc(CSc4cc(OCCCn5c(C(O)=O)c(Cl)c6c-2c(Cl)ccc56)c2ccccc2c4)n(C)n3)nn1C

InChI Key InChIKey=HXSAVOBSWNWLHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608351   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608351((Z)-13,15-dichloro-21,25,61-trimethyl- 11H,21H,61H...)
Affinity DataIC50:  14nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent