BDBM608364 (Z)-96-fluoro-13,15,21,25,61-pentamethyl- 11H,21H,61H-10-oxa-4,8-dithia-1(4,1)-indola- 2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 22

SMILES Cc1c-2c(CSCc3cc(CSc4cc(OCCCn5c(C(O)=O)c(C)c6c-2c(C)ccc56)c2ccc(F)cc2c4)n(C)n3)nn1C

InChI Key InChIKey=HHMBCXIHRGACQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608364   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608364((Z)-96-fluoro-13,15,21,25,61-pentamethyl- 11H,21H,...)
Affinity DataIC50:  15nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent