BDBM608365 (Z)-15-chloro-96-fluoro-21,25,61-trimethyl-13- (((1,1,1-trifluoro-N- methylmethyl)sulfonamido)methyl)- 11H,21H,61H-10-oxa-4,8-dithia-1(4,1)-indola- 2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 23
SMILES CN(Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CSCc5nn(C)c(C)c5-c5c(Cl)ccc2c15)nn4C)cc1cc(F)ccc31)S(=O)(=O)C(F)(F)F
InChI Key InChIKey=CCMRNGHHQFMRQO-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608365
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 16nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair