BDBM608365 (Z)-15-chloro-96-fluoro-21,25,61-trimethyl-13- (((1,1,1-trifluoro-N- methylmethyl)sulfonamido)methyl)- 11H,21H,61H-10-oxa-4,8-dithia-1(4,1)-indola- 2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 23

SMILES CN(Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CSCc5nn(C)c(C)c5-c5c(Cl)ccc2c15)nn4C)cc1cc(F)ccc31)S(=O)(=O)C(F)(F)F

InChI Key InChIKey=CCMRNGHHQFMRQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608365   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608365((Z)-15-chloro-96-fluoro-21,25,61-trimethyl-13- (((...)
Affinity DataIC50:  16nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent