BDBM608368 (Z)-15-chloro-96-fluoro-21,25,61-trimethyl-13- (trifluoromethyl)-11H,21H,61H-10-oxa-4,8- dithia-1(4,1)-indola-2(4,3),6(3,5)-dipyrazola- 9(3,1)-naphthalenacyclotridecaphane-12- carboxylic acid::US11691989, Compound 24

SMILES Cc1c-2c(CSCc3cc(CSc4cc(OCCCn5c(C(O)=O)c(c6c-2c(Cl)ccc56)C(F)(F)F)c2ccc(F)cc2c4)n(C)n3)nn1C

InChI Key InChIKey=HCAZBTJZZBIOSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608368   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608368((Z)-15-chloro-96-fluoro-21,25,61-trimethyl-13- (tr...)
Affinity DataIC50:  15nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent