BDBM608374 (Z)-15-chloro-96-fluoro-13,61-dimethyl-4- (methylsulfonyl)-26,27-dihydro-11H,24H,61H- 10-oxa-8-thia-4-aza-2(3,2)-pyrazolo[5,1- c][1,4]oxazina-1(4,1)-indola-6(3,5)-pyrazola- 9(3,1)-naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 30

SMILES Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CN(Cc5nn6CCOCc6c5-c5c(Cl)ccc2c15)S(C)(=O)=O)nn4C)cc1cc(F)ccc31

InChI Key InChIKey=IWUPMCGIHLYTQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608374   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608374((Z)-15-chloro-96-fluoro-13,61-dimethyl-4- (methyls...)
Affinity DataIC50:  17nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent