BDBM608375 (Z)-15-chloro-4-(cyclopropylsulfonyl)-96- fluoro-13,61-dimethyl-26,27-dihydro- 11H,24H,61H-10-oxa-8-thia-4-aza-2(3,2)- pyrazolo[5,1-c][1,4]oxazina-1(4,1)-indola- 6(3,5)-pyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 31
SMILES Cc1c(C(O)=O)n2CCCOc3cc(SCc4cc(CN(Cc5nn6CCOCc6c5-c5c(Cl)ccc2c15)S(=O)(=O)C1CC1)nn4C)cc1cc(F)ccc31
InChI Key InChIKey=GRXXZBQBEPHMLM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608375
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 16nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair