BDBM608387 (Z)-15-chloro-96-fluoro-13,21,25,61- tetramethyl-4-(oxazole-2-carbonyl)- 11H,21H,61H-10-oxa-8-thia-4-aza-1(4,1)- indola-2(4,3),6(3,5)-dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 43

SMILES Cc1c-2c(CN(Cc3cc(CSc4cc(OCCCn5c(C(O)=O)c(C)c6c-2c(Cl)ccc56)c2ccc(F)cc2c4)n(C)n3)C(=O)c2ncco2)nn1C

InChI Key InChIKey=XKIGKMNNEKHPGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 608387   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Human)
Ascentage Pharma (Suzhou)

US Patent
LigandPNGBDBM608387((Z)-15-chloro-96-fluoro-13,21,25,61- tetramethyl-4...)
Affinity DataIC50:  22nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent