BDBM608391 (Z)-15-chloro-13,21,25,61-tetramethyl-4- ((trifluoromethyl)sulfonyl)-11H,21H,61H-10- oxa-8-thia-4-aza-1(4,1)-indola-2(4,3),6(3,5)- dipyrazola-9(3,1)- naphthalenacyclotridecaphane-12-carboxylic acid::US11691989, Compound 47
SMILES Cc1c-2c(CN(Cc3cc(CSc4cc(OCCCn5c(C(O)=O)c(C)c6c-2c(Cl)ccc56)c2ccccc2c4)n(C)n3)S(=O)(=O)C(F)(F)F)nn1C
InChI Key InChIKey=RTOCQQUNNBUUTI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608391
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-323](Homo sapiens (Human))
Ascentage Pharma (Suzhou)
US Patent
Ascentage Pharma (Suzhou)
US Patent
Affinity DataIC50: 5nMAssay Description:The relative binding potency of representative Compounds of the Disclosure was determined by a fluorescence polarization (FP) assay. The method used ...More data for this Ligand-Target Pair